化工社化工社 化学情報印刷レポート · 研究参考用
3-Methyl-2-buten-1-OL → Ethyl 3,3-dimethylpent-4-enoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Methyl-2-buten-1-OL | HCID 11173 | — |
| 反応物 | Ethyl ortho-acetate | HCID 86598186 | — |
| 触媒 | Boric Acid | HCID 7628 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Ethyl 3,3-dimethylpent-4-enoate | HCID 82262 | 80.1% |
反応手順
A mixture of 4.3 g of 3-methyl-2-buten-1-ol, 16.2 g of ethyl orthoacetate and 86 mg of boric acid was heated for 2 hours at 120° with stirring, during which ethanol was evolved and removed. The temperature was then increased to 145°-150° where it was maintained for an additional 8 hours. When ethanol evolution ceased, the mixture was distilled to separate unreacted ethyl orthoacetate from 6.25 g (80% yield) of ethyl 3,3-dimethyl-4-pentenoate, b.p. 78°-80°/51 mm.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04999451 |
| 出典データセット | uspto-grants-1991_03 |
| ORD ID | ord-f83c2bee929a48e5808c646049e1d2ed |
| 出典メモ | uspto-grants-1991_03 |