Allylurea → Ethyl 2-(2-propenylamino)-4-(trifluoromethyl)-5-oxazolecarboxylate

関与物質

反応手順

By the procedure of Example 4, 6 g (60 mmol) of allyl urea was reacted with 10.9 g (50 mmol) of ethyl 2-chloro-4,4,4-trifluoroacetoacetate at 140°-150° C. for 18 hours. The product was separated and then recrystallized from methylcyclohexane to yield 4.77 g of a yellow solid product (m.p.=48°-49° C.) identified in Table I.

情報源と証拠