化工社化工社 化学情報印刷レポート · 研究参考用
Sulfuric Acid → 7-Hydroxy-4,6-dimethyl-2H-1-benzopyran-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | Ethyl Acetoacetate | HCID 8868 | — |
| 反応物 | 1,3-Benzenediol, 4-methyl- | HCID 10333 | — |
| 生成物 | 7-Hydroxy-4,6-dimethyl-2H-1-benzopyran-2-one | HCID 10797739 | — |
反応手順
A solution of 2,4-dihydroxytoluene (10.0 g) in ethylacetoacetate (12 ml) was poured in small portion into conc. H2SO4 (26 ml), chilling in an ice bath. After the addition was completed the solid obtained was separated by filtration, washed several times with water up to neutrality of the washings, dried and crystallized from MeOH, yielding 4,6-dimethyl-7-hydroxycoumarin (III) (10.64 g; m.p. 273° C.). ##STR9##
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05001147 |
| 出典データセット | uspto-grants-1991_03 |
| ORD ID | ord-d9d006fbc7f34f76bf56b49995c94735 |
| 出典メモ | uspto-grants-1991_03 |