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Benzoyl isothiocyanate → 2-[[(Benzoylamino)thioxomethyl)amino]-5-methylbenzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzoyl isothiocyanate | HCID 68284 | — |
| 反応物 | 2-Amino-5-methylbenzamide | HCID 10329436 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 2-[[(Benzoylamino)thioxomethyl)amino]-5-methylbenzamide | HCID 15135526 | 92.7% |
反応手順
To a stirred mixture of 4.5 g of 2-amino-5-methylbenzamide and 200 ml of ether was added dropwise, a solution of 4.9 g benzoyl isothiocyanate in 100 ml of ether over 20 minutes. After stirring overnight, the solid was collected, giving 8.7 g of the desired product as white crystals, mp 198°-201° C. (dec.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05001157 |
| 出典データセット | uspto-grants-1991_03 |
| ORD ID | ord-bf226b19b1494fbcb2fcb721767d0361 |
| 出典メモ | uspto-grants-1991_03 |