Benzoyl isothiocyanate → 2-[[(Benzylamino)thioxomethyl]amino]-N-phenylbenzamide

HRID 359539ノート

反応式

HRID 359539 の反応式
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[C:4]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[O:5].[C:17]([N:25]=[C:26]=[S:27])(=O)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>CCOCC>[CH2:17]([NH:25][C:26]([NH:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[C:4]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[O:5])=[S:27])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

参加物

4

反応物 2

HCID 68284Benzoyl isothiocyanateHCID 781422-Amino-N-phenylbenzamide

生成物 1

HCID 200651692-[[(Benzylamino)thioxomethyl]amino]-N-phenylbenzamide収率 1,015.8%

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒2 回

実験手順

To a stirred mixture of 1.0 g of 2-amino-N-phenylbenzamide and 500 ml of ether was added dropwise, a solution of 7.7 g of benzoyl isothiocyanate in 100 ml of ether over 20 minutes. After standing several hours, the solid was collected, giving 17.3 g of the desired product as cream- colored crystals mp 197°-200° C. (dec.).

後処理

  1. additionwas added dropwise
  2. waitAfter standing several hours
  3. customthe solid was collected

出典と根拠

ORDレコード
ord-8886c6374ee14ed0adc2d57d31ddb5d5
出典データセット
uspto-grants-1991_03
特許番号
US05001157

反応ノート

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