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Pentafluorobenzaldehyde → 2,3,4,5,6-Pentafluorobenzylidene rhodanine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Pentafluorobenzaldehyde | HCID 69558 | — |
| 反応物 | Rhodanine | HCID 1201546 | — |
| 反応物 | 2-Sulpho tetrafluorobenzoic acid | HCID 19807653 | — |
| 反応物 | 2-Fluorosulphonyl tetrafluorobenzoyl fluoride | HCID 19807656 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 溶媒 | Triethylamine | HCID 8471 | — |
| 生成物 | 2,3,4,5,6-Pentafluorobenzylidene rhodanine | HCID 4907291 | 73.8% |
反応手順
Production of 2-sulpho tetrafluorobenzoic acid ##STR61## and 2-fluorosulphonyl tetrafluorobenzoyl fluoride ##STR62## 38 g of triethylamine were added dropwise to a well stirred suspension of 50 g of rhodanine and 70 g of pentafluorobenzaldehyde in 100 ml of chloroform, the temperature being held below 40° C. by external cooling. After one hour, the solution was washed with dilute HCl, then water. The solvent was removed and the resultant yellow residue recrystallised from IMS/water to give 82 g of 2,3,4,5,6-pentafluorobenzylidene rhodanine having a melting point of 132-135° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05001163 |
| 出典データセット | uspto-grants-1991_03 |
| ORD ID | ord-0ec4dc541aa24db4ac752d485e614555 |
| 出典メモ | uspto-grants-1991_03 |