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Cetyl Alcohol → 8-(Hexadecyloxy)-7-methoxy-1-octene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cetyl Alcohol | HCID 2682 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | p-Toluenesulfonate | HCID 85570 | — |
| 反応物 | 8-Hydroxy-7-methoxy-1-octene | HCID 19939570 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 8-(Hexadecyloxy)-7-methoxy-1-octene | HCID 19939565 | — |
反応手順
To a suspension of 7.4 g of 60% sodium hydride in 100 ml of dimethylformamide was added a solution of 8-hydroxy-7-methoxy-1-octene in 150 ml of dimethylformamide over 1.5 hours. A 63.4 g portion of the tosylate of 1-hexadecanol was added and the mixture was stirred for 18 hours, poured into water and extracted with ether. The ether solution was dried and evaporated. The residue was purified by chromatography giving 41.5 g of the title compound as a oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05411983 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-95f61b892d9b4419a2ca820c0f9db754 |
| 出典メモ | uspto-grants-1995_05 |