Hydrochloric Acid → 3-Fluoro-2-methylthionaphthacene-5,12-dione

関与物質

反応手順

1 g (3.4 mmol) of 2,3-difluoronaphthacene-5,12-dione, 0.94 g (6.8 mmol) of potassium carbonate, 0.47 g (6.8 mmol) of sodium methanethiolate and 20 ml of tetrahydrofuran are stirred at 25° C. for 2.5 hours. The mixture is poured into dilute hydrochloric acid and extracted with THF/toluene. The organic phase is dried over sodium sulfate and evaporated. The residue is chromatographed on silica gel with toluene. Yield 0.55 g (50%); melting point 230°-235° C.

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