Hydrochloric Acid → HCID 20063614、化合物

HRID 359639ノート

反応式

HRID 359639 の反応式
[NH2:1][C:2]1[C:7]([O:8][CH3:9])=[C:6]([N+:10]([O-:12])=[O:11])[C:5]([O:13][CH3:14])=[CH:4][C:3]=1[O:15][CH3:16].C(=O)([O-])[O-].[Ca+2].Cl[C:23]([O:25][CH2:26][CH2:27][Cl:28])=[O:24].Cl>O1CCOCC1.O>[Cl:28][CH2:27][CH2:26][O:25][C:23]([NH:1][C:2]1[C:7]([O:8][CH3:9])=[C:6]([N+:10]([O-:12])=[O:11])[C:5]([O:13][CH3:14])=[CH:4][C:3]=1[O:15][CH3:16])=[O:24]

参加物

7

反応物 4

HCID 313Hydrochloric AcidHCID 10112Calcium CarbonateHCID 123052-Chloroethyl chloroformateHCID 23009735HCID 23009735、化合物

生成物 1

HCID 20063614HCID 20063614、化合物

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 312751,4-Dioxane溶媒

反応条件

温度
90 °C

実験手順

0.26 moles (60 g) of 2-amino-4-nitro-1,3,5-trimethoxybenzene are dissolved in 270 ml of dioxane. 26.3 g of calcium carbonate are added and the temperature is then raised to about 90° C. 0.34 moles (48.6 g) of chloroethyl chloroformate are then added with stirring. When the addition is complete, stirring is continued for additional 30 minutes at 90° C. The reaction mixture is diluted with 600 ml of iced water and is then acidified by adding 25 ml of concentrated hydrochloric acid. The precipitate obtained is filtered off and washed with water. After drying, it melts at 133° C.

後処理

  1. additionWhen the addition
  2. stirringstirring
  3. customThe precipitate obtained
  4. filtrationis filtered off
  5. washwashed with water
  6. customAfter drying

出典と根拠

ORDレコード
ord-d71af70884674198a4244e8928149e1c
出典データセット
uspto-grants-1991_03
特許番号
US05002585

反応ノート

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