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Methyl 4-bromobenzoate → 2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carboxylic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl 4-bromobenzoate | HCID 12081 | — |
| 反応物 | 5-phenyl-2-(2-phenylpropan-2-yl)-2H-tetrazole | HCID 1289594 | — |
| 触媒 | Nickel | HCID 935 | — |
| 生成物 | 2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carboxylic acid methyl ester | HCID 11825483 | — |
反応手順
reacting the ortho-transmetalated 2-(1-methyl-1-phenylethyl)-5-phenyl-2H-tetrazole with methyl 4-bromobenzoate in the presence of phosphinated nickel catalyst to give 2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carboxylic acid methyl ester,
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05412102 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-42668a80998344b19de3080d89fd669a |
| 出典メモ | uspto-grants-1995_05 |