Methyl 4-bromobenzoate → 2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carboxylic acid methyl ester

HRID 36037

反応式

HRID 36037 の反応式
[CH3:1][C:2]([N:10]1[N:14]=[N:13][C:12]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[N:11]1)([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[CH3:3].Br[C:22]1[CH:31]=[CH:30][C:25]([C:26]([O:28][CH3:29])=[O:27])=[CH:24][CH:23]=1>[Ni]>[CH3:29][O:28][C:26]([C:25]1[CH:30]=[CH:31][C:22]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=2[C:12]2[N:13]=[N:14][N:10]([C:2]([CH3:1])([C:4]3[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=3)[CH3:3])[N:11]=2)=[CH:23][CH:24]=1)=[O:27]

参加物

4

反応物 2

HCID 12081Methyl 4-bromobenzoateHCID 12895945-phenyl-2-(2-phenylpropan-2-yl)-2H-tetrazole

生成物 1

HCID 118254832'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carboxylic acid methyl ester

試薬・触媒・溶媒 1

HCID 935Nickel触媒

実験手順

reacting the ortho-transmetalated 2-(1-methyl-1-phenylethyl)-5-phenyl-2H-tetrazole with methyl 4-bromobenzoate in the presence of phosphinated nickel catalyst to give 2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carboxylic acid methyl ester,

出典と根拠

ORDレコード
ord-42668a80998344b19de3080d89fd669a
出典データセット
uspto-grants-1995_05
特許番号
US05412102

関連ノート

読み込み中…