alpha-Hydroxy-gamma-methylmercaptobutyric acid → 2-Hydroxy-4-(methylsulfanyl)butanamide

関与物質

反応手順

A further aspect of the present invention is directed to a process for the preparation of salts of 2-hydroxy-4-(methylthio)-butanoic acid from 2-hydroxy-4-(methylthio)-butanenitrile. 2-Hydroxy-4-(methylthio)-butanenitrile is enzymatically hydrated to form 2-hydroxy-4-(methylthio)-butaneamide, and the resulting 2-hydroxy-4-(methylthio)-butaneamide is hydrolyzed in a basic solution to form a salt of 2-hydroxy-4-(methylthio)-butanoic acid.

情報源と証拠