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Ethyl benzoylacetate → N-(6-methoxybenzothiazol-2-yl)-3-oxo-3-phenylpropanamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl benzoylacetate | HCID 7170 | — |
| 反応物 | 2-Amino-6-methoxybenzothiazole | HCID 15630 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | N-(6-methoxybenzothiazol-2-yl)-3-oxo-3-phenylpropanamide | HCID 19975336 | — |
反応手順
Ethyl benzoyl acetate (9.5 ml) and 2-amino-6-methoxy benzothiazole (9.01 g) are heated to 140° under house vacuum for 2 hours. After cooling, the residue is taken up in acetone and filtered. The precipitate is dissolved in hot DMF to give an amide, N-(6-methoxybenzothiazol -2-yl)-3-oxo-3-phenylpropanamide (II).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05412141 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-05a90fbe55264688b82f73bcc6384ff0 |
| 出典メモ | uspto-grants-1995_05 |