関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Nitric Acid | HCID 944 | — |
| 反応物 | 2,6-Dichloro-4'-methoxy-2'-methyl-benzophenone | HCID 54505258 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2,6-Dichloro-5'-nitro-4'-methoxy-2'-methyl-benzophenone | HCID 54492291 | — |
反応手順
2,6-Dichloro-4'-methoxy-2'-methyl-benzophenone (0.75 g; 2.5 mmol) is added to nitric acid (10 ml; 65%). The mixture is stirred at 80° C. for 1hour. After addition of water the reaction product crystallises and is chromatographically purified (flash column filled with 30 g of silicagel, elution with toluene). White crystals (0.35 g; 41% y); mp. 156°-160° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05866722 |
|---|
| 出典データセット | uspto-grants-1999_02 |
|---|
| ORD ID | ord-7ffdccfbac954e48aa3458fa8a6fa77a |
|---|
| 出典メモ | uspto-grants-1999_02 |
|---|
