Water → 1,1,7-TRICHLORO-1-HEPTEN-3-ONE

HRID 362660ノート

反応式

HRID 362660 の反応式
[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6](Cl)=[O:7].[Cl-].[Al+3].[Cl-].[Cl-].[Cl:13][C:14]([Cl:16])=[CH2:15].O>C(Cl)Cl>[Cl:13][C:14]([Cl:16])=[CH:15][C:6](=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2][Cl:1]

参加物

6

反応物 4

HCID 962WaterHCID 6366Vinylidene chlorideHCID 740895-Chlorovaleryl chlorideHCID 6451240Aluminum(III) Chloride

生成物 1

HCID 108568781,1,7-TRICHLORO-1-HEPTEN-3-ONE

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

実験手順

100 g (0.62 mol) 5-Chlorovaleroyl chloride was added dropwise to 78.53 g (0.589 mmol) aluminium chloride in 150 ml methylene chloride at room temperature. After stirring for 1 hour, 45 ml (0.558 mol) 1,1-dichloroethylene in 25 ml methylene chloride was added dropwise. Under ice-cooling 100 ml water was added dropwise and solid material suction filtered on Celite. The filtrate was washed with water and the organic phase dried and concentrated. The residue was distilled in a rotary evaporator.

後処理

  1. additionwas added dropwise
  2. filtrationsolid material suction filtered on Celite
  3. washThe filtrate was washed with water
  4. customthe organic phase dried
  5. concentrationconcentrated
  6. distillationThe residue was distilled in a rotary evaporator

出典と根拠

ORDレコード
ord-28f460e647064d609373f3b7abc6c5b6
出典データセット
uspto-grants-1999_02
特許番号
US05869686

反応ノート

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