(E)-2-(4,6-difluoro-1-indanylidene)acetic acid → (E)-2-(4-fluoro-1-indanylidene)acetyl Chloride

HRID 362833ノート

反応式

HRID 362833 の反応式
[F:1][C:2]1[CH:10]=[C:9](F)[CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5]/[C:6]/2=[CH:12]\[C:13]([Cl:15])=[O:14].FC1C=C(F)C=C2C=1CC/C/2=C\C(O)=O>>[F:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][CH2:5]/[C:6]/2=[CH:12]\[C:13]([Cl:15])=[O:14]

参加物

3

反応物 2

HCID 10976722(E)-2-(4,6-difluoro-1-indanylidene)acetic acidHCID 10977254(E)-2-(4,6-difluoro-1-indanylidene)acetyl Chloride

生成物 1

HCID 23293683(E)-2-(4-fluoro-1-indanylidene)acetyl Chloride

実験手順

This compound was prepared in a similar manner to (E)-2-(4,6difluoro-1-indanylidene)acetyl chloride in Example 5f by substituting (E)-2-(4-fluoro-1-indanylidene)acetic acid (5.77 g, 0.03 mol) for (E)-2-(4,6-difluoro-1-indanylidene)acetic acid. The resulting solution was concentrated in vacuo, and the residue was used without further purification.

後処理

  1. concentrationThe resulting solution was concentrated in vacuo
  2. customthe residue was used without further purification

出典と根拠

ORDレコード
ord-04a18eb498ce4517b85679760aa991e6
出典データセット
uspto-grants-1999_02
特許番号
US05872118

反応ノート

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