4-(Benzyloxy)phenyl benzoate → p-Hydroxyphenyl benzoate

HRID 363089

反応式

HRID 363089 の反応式
[C:1]([O:9][C:10]1[CH:15]=[CH:14][C:13]([O:16]CC2C=CC=CC=2)=[CH:12][CH:11]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H][H]>[C].[Pd].C(O)C>[C:1]([O:9][C:10]1[CH:11]=[CH:12][C:13]([OH:16])=[CH:14][CH:15]=1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

5

反応物 2

HCID 2412554-(Benzyloxy)phenyl benzoateHCID 178418361HCID 178418361、化合物2 回

生成物 1

HCID 75549p-Hydroxyphenyl benzoate収率 94%

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 702Ethanol溶媒

実験手順

A reaction vessel was charged with 38 g of 4-benzyloxyphenyl benzoate and 500 ml of ethanol, and the air in the vessel was replaced with nitrogen. Then, 1.0 g of 10% palladium carbon was added thereto, and the nitrogen in the vessel was replaced with hydrogen, followed by vigorous stirring at room temperature for 24 hours. The hydrogen in the vessel was replaced with nitrogen, after which the reaction mixture was filtered though celite, and the filtrate was concentrated, which afforded 24.5 g of 4-hydroxyphenyl benzoate (94% yield).

後処理

  1. filtrationafter which the reaction mixture was filtered though celite
  2. concentrationthe filtrate was concentrated

出典と根拠

ORDレコード
ord-a929d519d72544c49f384c6363083c0c
出典データセット
uspto-grants-1999_02
特許番号
US05872137

関連ノート

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