化工社化工社 化学情報印刷レポート · 研究参考用
Sulfuric Acid → Azelaic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 8-Cyano-octanoic acid | HCID 11084300 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Dimethyl ether ethylene glycol | HCID 21863332 | — |
| 生成物 | Azelaic Acid | HCID 2266 | — |
反応手順
83.5 g of 8-cyanooctanoic acid dissolved in 300 ml of dimethyl ether ethylene glycol are heated to 130° C. for 4 hours in the presence of 50g of 40% caustic soda. After cooling, the reaction mixture is diluted with water, then acidified to pH 5 with diluted sulfuric acid, and then the precipitated solid is filtered. After drying, 92 g of azelaic acid with a m.p. of 107° C. are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05872267 |
| 出典データセット | uspto-grants-1999_02 |
| ORD ID | ord-106c0db6ab624e2f871a05c8c526b87c |
| 出典メモ | uspto-grants-1999_02 |