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Sodium Iodide → Iodomethyl hexanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Iodide | HCID 5238 | — |
| 反応物 | Iodomethyl pivalate | HCID 104401 | — |
| 反応物 | Chloromethyl hexanoate | HCID 525229 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | Iodomethyl hexanoate | HCID 12775069 | 78% |
反応手順
Chloromethyl hexanoate (205 mg, 1.25 mmol) was stirred with sodium iodide (900 mg, 6.0 mmol) in 3 mL of dry acetone for 4 hours at room temperature. Work-up followed the procedure detailed in EXAMPLE 3 above for the preparation of iodomethyl pivalate. Iodomethyl hexanoate, CH3 (CH2)4COOCH2I, was obtained as a yellow oil in 78% yield. NMR values were consistent with the assigned structure.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05413996 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-f26bb85210104c488af55ec157d8b6d1 |
| 出典メモ | uspto-grants-1995_05 |