関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Phosphorus tribromide | HCID 24614 | — |
| 反応物 | 3-Chlorobenzyl alcohol | HCID 70117 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 1-(Bromomethyl)-3-chlorobenzene | HCID 69838 | — |
反応手順
A solution of 260 ul of 3-chlorobenzyl alcohol dissolved in 2.5 ml of dry tetrahydrofuran is cooled to 0° C. and 120 ul of PBr3 added. The reaction is stirred for 3 hours and extracted with ether. The organic layer is washed with saturated sodium bicarbonate and evaporated to give the desired product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05414001 |
|---|
| 出典データセット | uspto-grants-1995_05 |
|---|
| ORD ID | ord-2e356bec6541419499a7e4e5503f2522 |
|---|
| 出典メモ | uspto-grants-1995_05 |
|---|
