tetrahydrofuran N-(13-benzyloxycarbonyltridecanoyloxy)succinimide → HCID 9928580、化合物

HRID 36391ノート

反応式

HRID 36391 の反応式
C([O:8][C:9]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23]([O:25][N:26]1[C:30](=[O:31])[CH2:29][CH2:28][C:27]1=[O:32])=[O:24])=[O:10])C1C=CC=CC=1.O1CCCC1>[C].[Pd]>[C:9]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23]([O:25][N:26]1[C:30](=[O:31])[CH2:29][CH2:28][C:27]1=[O:32])=[O:24])([OH:10])=[O:8]

参加物

3

反応物 1

HCID 21832384tetrahydrofuran N-(13-benzyloxycarbonyltridecanoyloxy)succinimide

生成物 1

HCID 9928580HCID 9928580、化合物収率 94%

試薬・触媒・溶媒 1

HCID 178418390HCID 178418390、化合物触媒

実験手順

In 15 ml of tetrahydrofuran N-(13-benzyloxycarbonyltridecanoyloxy)succinimide (2.28 g, 5.12 mmoles) was dissolved. To the obtained solution, were added 228 mg of 10% palladium carbon and the mixture was stirred for 15 hours under an atmosphere of hydrogen. The reaction mixture was filtered and the filtrate was concentrated under reduced pressure. The residue was recrystallized from ethanol, to give N-(13-carboxytridecanoyloxy)succinimide (1.71 mg, 94%) having the following properties.

後処理

  1. filtrationThe reaction mixture was filtered
  2. concentrationthe filtrate was concentrated under reduced pressure
  3. customThe residue was recrystallized from ethanol

出典と根拠

ORDレコード
ord-d0272ec0bd3a4822a08e2a60070ec05f
出典データセット
uspto-grants-1995_05
特許番号
US05414089

反応ノート

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