Tetrabutylammonium Hydroxide → Tetrabutylammonium

HRID 36403

反応式

HRID 36403 の反応式
[I:1][C:2]1[N:10]=[C:9]([NH2:11])[N:8]=[C:7]2[C:3]=1[NH:4][CH:5]=[N:6]2.[OH-].[CH2:13]([N+:17]([CH2:26][CH2:27][CH2:28][CH3:29])([CH2:22][CH2:23][CH2:24][CH3:25])[CH2:18][CH2:19][CH2:20][CH3:21])[CH2:14][CH2:15][CH3:16]>C(Cl)Cl>[CH2:26]([N+:17]([CH2:13][CH2:14][CH2:15][CH3:16])([CH2:18][CH2:19][CH2:20][CH3:21])[CH2:22][CH2:23][CH2:24][CH3:25])[CH2:27][CH2:28][CH3:29].[I:1][C:2]1[N:10]=[C:9]([NH2:11])[N:8]=[C:7]2[C:3]=1[NH:4][CH:5]=[N:6]2

参加物

5

反応物 2

HCID 2723671Tetrabutylammonium HydroxideHCID 61015752-Amino-6-iodopurine

生成物 2

HCID 16028TetrabutylammoniumHCID 61015752-Amino-6-iodopurine

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

To a mixture of 6-iodo-2-aminopurine (1.21 g., 4.637 mmole) in methylene chloride (12 ml.) at room temperature, was added 1.5M tetra (n-butyl) ammonium hydroxide (2.7 ml., 4.05 mmole). The reaction mixture was stirred for 10 minutes, and the volatiles were removed in vacuo. Methylene chloride (12 ml.) was added to the white residue, and the resulting solution was dried (magnesium sulfate), filtered, and the filtrate was concentrated in vacuo to yield the tetra (n-butyl) ammonium salt of 6-iodo-2-aminopurine as a white residue.

後処理

  1. customthe volatiles were removed in vacuo
  2. additionMethylene chloride (12 ml.) was added to the white residue
  3. dry with materialthe resulting solution was dried (magnesium sulfate)
  4. filtrationfiltered
  5. concentrationthe filtrate was concentrated in vacuo

出典と根拠

ORDレコード
ord-ff24a0a11ce64d469f24a62f0589b726
出典データセット
uspto-grants-1995_05
特許番号
US05414096

関連ノート

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