化工社化工社 化学情報印刷レポート · 研究参考用
(3,4-Dimethoxyphenyl)acetic acid → (3,4-Dimethoxyphenyl)acetyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (3,4-Dimethoxyphenyl)acetic acid | HCID 7139 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | (3,4-Dimethoxyphenyl)acetyl chloride | HCID 3604458 | — |
反応手順
Thionyl chloride (600 ml) is added dropwise, with stirring, over a period of 2 hours, to a suspension of 3,4-dimethoxy-phenylacetic acid (549.4 g) in methylene chloride (600 ml). After the development of gas has ended (16 hours) the mixture is refluxed for a further hour. After the highly volatile components have been removed the residue is distilled in vacuo.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04604389 |
| 出典データセット | uspto-grants-1986_08 |
| ORD ID | ord-84c79170daf541418aa1ecc3cbc7f128 |
| 出典メモ | uspto-grants-1986_08 |