関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Heptafluorobutyryl Chloride | HCID 67810 | — |
| 反応物 | Silane, tris(1-methylethyl)- | HCID 138754 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 生成物 | Heptafluorobutyraldehyde | HCID 67809 | 64.4% |
反応手順
A 3-necked round bottom flask fitted with dropping funnel, dry-ice condenser, and gas inlet was charged with 10% Pd/C(0.35 g) and cooled to 0° C. Triisopropylsilane (7.29 g, 46 mmol) was added, and CF3CF2CF2C(O)Cl (9.30 g, 40 mmol) was added dropwise over a 10 min period. The reactor was connected to a cold trap (-78° C.) while the mixture was stirred for 18 hr. Transfer from the trap and reaction vessel gave a total of 5.1 g (62%) of colorless liquid. 1H NMR (CD2Cl2): 9.62 (m). 19F NMR: -81.24 (t, J=8.3 Hz), -126.4 (quartet of doublets, Jq =8.3, Jd =3.2), -127.9 (s).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US05414140 |
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| 出典データセット | uspto-grants-1995_05 |
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| ORD ID | ord-10a3cd1bb37642bd9b0560357400337e |
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| 出典メモ | uspto-grants-1995_05 |
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