Phenol → 2-Isopropylphenol

HRID 36478

反応式

HRID 36478 の反応式
C1(O)C=CC=CC=1.[CH:8]([C:11]1[CH:16]=[CH:15][CH:14]=[C:13](C(C)C)[C:12]=1[OH:20])([CH3:10])[CH3:9]>[O-]C1C=CC=CC=1.[Al+3].[O-]C1C=CC=CC=1.[O-]C1C=CC=CC=1>[CH:8]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[OH:20])([CH3:10])[CH3:9]

参加物

4

反応物 2

HCID 996PhenolHCID 4943Propofol

生成物 1

HCID 69432-Isopropylphenol収率 11.3%

試薬・触媒・溶媒 1

HCID 167236Phenol, aluminum salt (3:1)触媒

実験手順

For example, U.S. Pat. No. 2,831,898 discloses a process for producing 2,6-diisopropyl phenol from propylene gas and phenol by Friedel-Crafts reaction at high pressure of 21-35 atm, high temperature of 200°-210° C. and under nitrogen atmosphere with aluminum phenoxide, as a catalyst, prepared from alumina and phenol. But there is a defect that 2,6-diisopropyl phenol desired was obtained only with 11.3% yield even though 2-isopropyl phenol which is a by-product was obtained with 31.4% yield.

後処理

  1. customby Friedel-Crafts reaction at high pressure of 21-35 atm, high temperature of 200°-210° C.

出典と根拠

ORDレコード
ord-ecc444f57693423e9e56e8881183e4e1
出典データセット
uspto-grants-1995_05
特許番号
US05414156

関連ノート

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