Hydrochloric Acid → 3-Cyclohexen-1-ol, 1-(1-chloro-1-methylethyl)-4-methyl-

HRID 364830ノート

反応式

HRID 364830 の反応式
[CH3:1][C:2]1([CH3:11])[C:4]2([CH2:9][CH2:8][C:7]([CH3:10])=[CH:6][CH2:5]2)[O:3]1.[ClH:12]>C(OCC)C>[CH3:10][C:7]1[CH2:8][CH2:9][C:4]([C:2]([Cl:12])([CH3:11])[CH3:1])([OH:3])[CH2:5][CH:6]=1

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 1073032,2,6-Trimethyl-1-oxaspiro(2.5)oct-5-ene

生成物 1

HCID 1590433-Cyclohexen-1-ol, 1-(1-chloro-1-methylethyl)-4-methyl-

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

To a stirred solution of 15.2 g of 2,2,6-trimethyl-1-oxaspiro(2.5)oct-5-ene in 200 ml of diethyl ether held at -10° C. was added dropwise 32 ml of 3.8N ethereal hydrogen chloride. After one hour at 0°-5° C., the mixture was washed with three 50 ml portions of water, dried and distilled to give 14.5 g of the desired product, b.p. 70°-75° C. (0.4 mm).

後処理

  1. customheld at -10° C.
  2. washthe mixture was washed with three 50 ml portions of water
  3. customdried
  4. distillationdistilled

出典と根拠

ORDレコード
ord-f350b3afda104eb4b8ceba62f2b4df4a
出典データセット
uspto-grants-1986_08
特許番号
US04606753

反応ノート

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