Ammonia → Naphthalenesulfonamide
反応式
[NH3:1].[C:2]1([S:12](Cl)(=[O:14])=[O:13])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][CH:3]=1>CCOCC>[C:2]1([S:12]([NH2:1])(=[O:14])=[O:13])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][CH:3]=1参加物
4
実験手順
Ammonia was passed (for 5 min) into a stirred solution of 1-naphthalenesulfonyl chloride (5.0 g, 22 mmol) and anhydrous Et2O (400 ml) at -78°. The resulting mixture was stirred at -78° for 1 hr, allowed to warm to room temperature, and stirred overnight. The Et2O was removed under vacuum to leave a white powder which was washed with water and dried under vacuum to give 3.2 g (70%) of the title compound as a white powder, m.p. 152°-153° C.
後処理
- custom(for 5 min)
- customat -78°
- stirringstirred overnight
- customThe Et2O was removed under vacuum
- customto leave a white powder which
- washwas washed with water
- customdried under vacuum
出典と根拠
- ORDレコード
- ord-fadaa888f4d948e299b2e4650725ef94
- 出典データセット
- uspto-grants-1995_05
- 特許番号
- US05414132
反応ノート
読み込み中…