化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Carbonate → 4-Aminocarbonylphenoxyacetic acid methylester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Methyl bromoacetate | HCID 60984 | — |
| 反応物 | 4-Hydroxybenzamide | HCID 65052 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 4-Aminocarbonylphenoxyacetic acid methylester | HCID 8607870 | 63% |
反応手順
A mixture of p-hydroxybenzamide (3.43 g), methyl bromoacetate (2.37 ml) and K2CO3 (3.45 g) was stirred for 12 hr in 25 ml of DMF. The reaction mixture was diluted with water (150 ml); the solid was filtered, washed with water, and air dried. Crystallization from ethanol gave 3.3 g (63%) of the title compound as white crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05414132 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-660078129add4fc29c165ea2d40c339c |
| 出典メモ | uspto-grants-1995_05 |