Ammonia → 5-(Tert-butyl)-2-methoxybenzenesulfonamide
反応式
[CH3:1][C:2]([C:5]1[CH:6]=[C:7]([S:13](Cl)(=[O:15])=[O:14])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1)([CH3:4])[CH3:3].[NH3:17]>CC(C)=O>[CH3:1][C:2]([C:5]1[CH:6]=[C:7]([S:13]([NH2:17])(=[O:15])=[O:14])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1)([CH3:4])[CH3:3]参加物
4
実験手順
25.3 g (0.1 mole) of 3-(1,1-dimethylethyl)-6-methoxybenzenesulfonyl chloride are dissolved in a little acetone and the solution is added dropwise slowly, at room temperature, to 100 ml of concentrated ammonia solution. The mixture is stirred for 30 minutes at room temperature and poured into ice water. After acidification with concentrated hydrochloric acid the product is filtered off with suction. It is recrystallized from isopropanol.
後処理
- filtrationAfter acidification with concentrated hydrochloric acid the product is filtered off with suction
- customIt is recrystallized from isopropanol
出典と根拠
- ORDレコード
- ord-837fffe468e44291a343d2f26f760701
- 出典データセット
- uspto-grants-1986_08
- 特許番号
- US04607030
反応ノート
読み込み中…