関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Chlorosulfonic acid | HCID 24638 | — |
| 反応物 | 6-Methoxytetralin | HCID 74414 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 3-Methoxy-5,6,7,8-tetrahydronaphthalene-2-sulfonyl chloride | HCID 13210342 | — |
反応手順
118 g (0.73 mole) of 5,6,7,8-tetrahydro-2-naphthol methyl ether are dissolved in 320 ml of methylene chloride, and 177 ml of chlorosulfonic acid in 160 ml of methylene chloride are added. The mixture is stirred for 10 minutes at 5° C. and is poured into ice water. The organic phase is separated off and dried with MgSO4. The solvent is removed by evaporation and the residue is recrystallized from acetone/petroleum ether.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04607030 |
|---|
| 出典データセット | uspto-grants-1986_08 |
|---|
| ORD ID | ord-9bacb43ee4cb43199d5ffc4dd58e4573 |
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| 出典メモ | uspto-grants-1986_08 |
|---|
