関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1-Chloro-4-(trifluoromethyl)benzene | HCID 7394 | — |
| 反応物 | Allyl Alcohol | HCID 7858 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 溶媒 | Sulfolane | HCID 31347 | — |
| 生成物 | Propenyl 4-trifluoromethylphenyl ether | HCID 86740963 | 68% |
反応手順
174 g of allyl alcohol was added to a mixture of 298 g of 85% flake potassium hydroxide and 750 ml of sulpholane under nitrogen, and the mixture was heated to 125°-135° C. 272 g of 4-chlorobenzotrifluoride was added over 20 minutes at this temperature. After 2 hours, the reaction mixture was cooled to 30° C., and distillation from the solvent gave 207 g of propenyl 4-trifluoromethylphenyl ether b.p.: 84°-88° C. at 15 Torr.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04607128 |
|---|
| 出典データセット | uspto-grants-1986_08 |
|---|
| ORD ID | ord-be72b45bf65b4194a2433b74d140fc6c |
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| 出典メモ | uspto-grants-1986_08 |
|---|
