Imidazole → HCID 13672864、化合物

HRID 365165ノート

反応式

HRID 365165 の反応式
[NH:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.Br[CH:7]([CH2:11][CH2:12][CH2:13][CH3:14])[C:8](=[O:10])[CH3:9].O>CN(C)C=O>[N:1]1([CH:7]([CH2:11][CH2:12][CH2:13][CH3:14])[C:8](=[O:10])[CH3:9])[CH:5]=[CH:4][N:3]=[CH:2]1

参加物

5

反応物 3

HCID 795ImidazoleHCID 962WaterHCID 125380843-Bromoheptan-2-one

生成物 1

HCID 13672864HCID 13672864、化合物

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

30 g of imidazole was dissolved in 80 ml of N,N-dimethylformamide. To this solution, 30 g of 3-bromo-2-heptanone was gradually added under stirring, and stirred at a temperature of from 50° to 60° C. for 4 hours. Then, the mixture was poured into water and extracted with chloroform. The extraction solution was treated by a usual manner, and the obtained oily product was purified by distillation, whereby 3-(imidazole-1-yl)-2-heptanone was obtained. The boiling point was 116°-119° C./2 mmHg.

後処理

  1. stirringstirred at a temperature of from 50° to 60° C. for 4 hours
  2. extractionextracted with chloroform
  3. additionThe extraction solution was treated by a usual manner
  4. distillationthe obtained oily product was purified by distillation

出典と根拠

ORDレコード
ord-de9a42574a3c4c8fa8723b20b29c40da
出典データセット
uspto-grants-1986_08
特許番号
US04608438

反応ノート

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