化工社化工社 化学情報印刷レポート · 研究参考用
1,2-Dimethylhydrazine → 3-Hydroxy-1,2,4-trimethyl-5-pyrazolone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,2-Dimethylhydrazine | HCID 1322 | — |
| 反応物 | Diethyl methylmalonate | HCID 11857 | — |
| 反応物 | Sodium Methoxide | HCID 10942334 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 3-Hydroxy-1,2,4-trimethyl-5-pyrazolone | HCID 12818853 | — |
反応手順
Diethyl methylmalonate and N,N'-dimethylhydrazine are heated under reflux for 170 hours in methanol in the presence of sodium methylate under an atmosphere of nitrogen. 3-Hydroxy-1,2,4-trimethyl-5-pyrazolone is obtained in the form of colorless crystals which, after recrystallization from ethyl acetate, melt at 87°-89° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04608383 |
| 出典データセット | uspto-grants-1986_08 |
| ORD ID | ord-da58efdd8cfd44639ad1ce4e0173a134 |
| 出典メモ | uspto-grants-1986_08 |