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Thionyl Chloride → 3-(3-Pyridyl)acryloyl chloride hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 3-(3-Pyridinyl)-2-propenoic acid | HCID 101984 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | 3-(3-Pyridyl)acryloyl chloride hydrochloride | HCID 71360027 | — |
反応手順
67 ml of benzene was added to 10 grams of 3-(3-pyridyl)-acrylic acid. 8.1 ml of thionyl chloride was added dropwise slowly thereto at ambient temperature. The temperature was elevated to 70° C. and the heating was continued until foaming ceased. Benzene and thionyl chloride were distilled off and the residue was dried thoroughly under reduced pressure.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05415780 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-c47a2810ac0e4dcd8f71084b2669a25f |
| 出典メモ | uspto-grants-1995_05 |