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Citric Acid → DL-Malate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Citric Acid | HCID 311 | — |
| 反応物 | Malic Acid | HCID 525 | — |
| 反応物 | delta-Gluconolactone | HCID 7027 | — |
| 反応物 | Sodium Bicarbonate | HCID 516892 | — |
| 生成物 | DL-Malate | HCID 160434 | — |
| 生成物 | Monosodium Citrate | HCID 23666341 | — |
反応手順
Process: Apply crystallized citric acid, then heat to 60° C. and wet with 36 ml of gluconic acid delta-lactone solution (10 parts of gluconic acid delta-lactone to 5 parts of water); apply malic acid, then allow sodium bicarbonate I to react to give monosodium citrate and malate and then allow sodium bicarbonate II, calcium carbonate and potassium bicarbonate to undergo partial reaction (partial conversion to the citrate). Then cover the surface with citric acid powder. Finally allow sodium carbonate to undergo partial reaction, and dry in vacuo. This effervescent base is mixed with 500 parts of aspirin and with corresponding additives.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05415870 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-b21f295b723640c999e6fa015768ecb3 |
| 出典メモ | uspto-grants-1995_05 |