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Bromoacetyl chloride → 4-Bromoacetyl-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Bromoacetyl chloride | HCID 89602 | — |
| 反応物 | 7-Methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine | HCID 11805628 | — |
| 溶媒 | Triethylamine | HCID 8471 | — |
| 生成物 | 4-Bromoacetyl-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine | HCID 15291645 | 51.5% |
反応手順
7-Methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine (3.0 g), triethylamine (3.1 g) and bromoacetyl chloride (3.2 g) were reacted in the same manner as in Experimental Example 1 to give 4-bromoacetyl-7-methoxy-2,3,4,5-tetrahydro-1,4-benzothiazepine (2.5 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05416066 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-f2d9bc7a547848ad9da613d6416d1ac8 |
| 出典メモ | uspto-grants-1995_05 |