関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1,2-Bis(chloromethyl)benzene | HCID 11919 | — |
| 反応物 | Phthalimide potassium salt | HCID 24194345 | — |
| 生成物 | N-(2-chloromethylbenzyl)phthalimide | HCID 57925620 | — |
反応手順
A mixture of α,α'-dichloroxylene (8.75 g, 50 mmol) and potassium phthalimide (5.6 g, 30 mmol) was heated to 50° C. for 24 h. Then the reaction mixture was concentrated in vacuo, dissolved in ethyl acetate and, after usual work-up, the desired compound was obtained by flash chromatography on silica gel (ethyl acetate:hexane; 15:85) (6 g, 65%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05416076 |
|---|
| 出典データセット | uspto-grants-1995_05 |
|---|
| ORD ID | ord-83c234a702b148d187820f5614fe44cc |
|---|
| 出典メモ | uspto-grants-1995_05 |
|---|
