Hydrochloric Acid → 2-Amino-1,1-dimethylethyl acetate hydrochloride

HRID 366207ノート

反応式

HRID 366207 の反応式
[C:1]([O:4][C:5]([CH3:16])([CH3:15])[CH2:6][NH:7]C(OC(C)(C)C)=O)(=[O:3])[CH3:2].[ClH:17]>C(OCC)(=O)C>[ClH:17].[C:1]([O:4][C:5]([CH3:16])([CH3:15])[CH2:6][NH2:7])(=[O:3])[CH3:2]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 208271532-(Tert-butoxycarbonylamino)-1,1-dimethylethyl acetate

生成物 1

HCID 865873402-Amino-1,1-dimethylethyl acetate hydrochloride

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒2 回

実験手順

2-(tert-Butoxycarbonylamino)-1,1-dimethylethyl acetate (508 mg, 2.2 mmol) was dissolved in ethyl acetate (6 ml). 3 M hydrogen chloride in ethyl acetate (4 ml, 12 mmol) was added. The reaction mixture was stirred for 20 h at room temperature. The precipitation was filltered off and washed with diethyl ether (50 ml). It was dried in vacuo to give 246 mg of 2-amino-1,1-dimethylethyl acetate hydrochloride.

後処理

  1. customThe precipitation
  2. washwashed with diethyl ether (50 ml)
  3. customIt was dried in vacuo

出典と根拠

ORDレコード
ord-0f74e6006ea349f988da14230b2d9eaa
出典データセット
uspto-grants-2000_10
特許番号
US06127391

反応ノート

読み込み中…