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1-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)piperazine → HCID 23289234、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)piperazine | HCID 2735936 | — |
| 反応物 | Dioxane toluene | HCID 21840791 | — |
| 反応物 | 2-Methyl-7-(7-oxa-bicyclo[4.1.0]hept-2-yloxy)-benzothiazole | HCID 23289293 | — |
| 反応物 | 4-Bromo-2-oxa-bicyclo[4.1.0]heptane | HCID 23289331 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | HCID 23289234 | HCID 23289234 | — |
| 生成物 | 2-Methyl-7-(7-oxa-bicyclo[4.1.0]hept-2-yloxy)-benzothiazole | HCID 23289293 | — |
反応手順
The title compound was prepared according to Method A from 2-methyl-7-(7-oxa-bicyclo[4.1.0]hept-2-yloxy)-benzothiazole and 1-(10,11-dihydro-5H-dibenzo[a,d]-cyclohepten-5-yl)piperazine with dioxane/toluene (2:1) as the solvent. mp 207° C. (decomposition); LSIMS m/z 540. The 2-methyl-7-(7-oxa-bicyclo[4.1.0]hept-2-yloxy)-benzothiazole was prepared according to Method IV using THF as the solvent and 4-bromo-2-oxa-bicyclo[4.1.0]heptane as the alkylating agent.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06130217 |
| 出典データセット | uspto-grants-2000_10 |
| ORD ID | ord-67ee121c137b4d01a6ddf9c39fb83777 |
| 出典メモ | uspto-grants-2000_10 |