2-Bromo-1-(4-hydroxyphenyl)ethanone → 4-(2-Pyridin-2-yl-thiazol-4-yl)phenol hydrobromide

HRID 366449

反応式

HRID 366449 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[S:8][CH:9]=[C:10]([C:12]2[CH:17]=[CH:16][C:15]([OH:18])=[CH:14][CH:13]=2)[N:11]=1.C1C(C(C[Br:28])=O)=CC=C(O)C=1.N1C=CC=CC=1C(N)=S>>[BrH:28].[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[S:8][CH:9]=[C:10]([C:12]2[CH:17]=[CH:16][C:15]([OH:18])=[CH:14][CH:13]=2)[N:11]=1

参加物

4

反応物 3

HCID 49642-Bromo-1-(4-hydroxyphenyl)ethanoneHCID 1549499Pyridine-2-carbothioamideHCID 232892604-(2-Pyridin-2-yl-thiazol-4-yl)phenol

生成物 1

HCID 232892594-(2-Pyridin-2-yl-thiazol-4-yl)phenol hydrobromide

実験手順

4-(2-Pyridin-2-yl-thiazol-4-yl)phenol hydrobromidewas preparedfrom α-bromo-4-hydroxyacetophenone and thiopicolinamide as described in Preparation 48; m.p. 261-262° C.

後処理

  1. customas described in Preparation 48

出典と根拠

ORDレコード
ord-cb76f3756aba4075afde132627c20e3e
出典データセット
uspto-grants-2000_10
特許番号
US06130217

関連ノート

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