2-(1-Cyclohexenyl)ethylamine → 3-[2-(Cyclohexen-1-yl)ethyl]-3-azabicyclo[3.1.0]hexane-2,4-dione
反応式
[C:1]1([CH2:7][CH2:8][NH2:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]=1.[CH:10]12[CH2:15][CH:14]1[C:13](=[O:16])[O:12][C:11]2=O>>[C:1]1([CH2:7][CH2:8][N:9]2[C:11](=[O:12])[CH:10]3[CH:14]([CH2:15]3)[C:13]2=[O:16])[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]=1参加物
3
反応条件
- 温度
- 180 °C
実験手順
A mixture of 2-(cyclohexen-1-yl)ethylamine (0.59 g) and 3-oxabicyclo[3.1.0]hexane-2,4-dione (0.5 g) was heated at 180° C. for 3 hours. The resulting mixture was cooled to room temperature to give the title compound as a yellow solid, m.p. 60-61° C.
後処理
- temperatureThe resulting mixture was cooled to room temperature
出典と根拠
- ORDレコード
- ord-eadb4d5121e74d88882f774216a6179b
- 出典データセット
- uspto-grants-2000_10
- 特許番号
- US06130241
反応ノート
読み込み中…