化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl chloroformate → Ethyl 2,2-dimethoxyethylcarbamate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl chloroformate | HCID 10928 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Aminoacetaldehyde dimethyl acetal | HCID 89728 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | Ethyl 2,2-dimethoxyethylcarbamate | HCID 10921057 | — |
反応手順
214 g (2 mol) of ethyl chloroformate are added dropwise to 214 g (2 mol) of aminoacetaldehyde dimethyl acetal in 1 l of toluene and 90 g of NaOH in 500 ml of water at 10° C. The mixture is stirred at room temperature for a further 2 hours and the aqueous phase is separated off, saturated with sodium chloride and extracted with toluene. The toluene solutions are dried over magnesium sulphate and concentrated and the residue is distilled.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05416096 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-9d97b7ac3ac0435c8feda74e2c76dc3b |
| 出典メモ | uspto-grants-1995_05 |