化工社化工社 化学情報印刷レポート · 研究参考用
Nitrogen → Acrylamidomethyl 2-oxopyrrolidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Nitrogen | HCID 947 | — |
| 反応物 | Acrylamide | HCID 6579 | — |
| 反応物 | 2-Methylbenzenesulfonic acid | HCID 6925 | — |
| 反応物 | Phenothiazine | HCID 7108 | — |
| 反応物 | 1-(Methoxymethyl)-2-pyrrolidinone | HCID 13624830 | — |
| 生成物 | Acrylamidomethyl 2-oxopyrrolidine | HCID 18414899 | 40% |
反応手順
The mixture of 1-methoxy methyl-2-pyrrolidone (65.6 g), acrylamide (75.5 g), toluene sulfonic acid (0.20 g) and phenothiazine (0.20 g) was stirred under the condition of N2 for 1 hour at 150° C. while removing methanol by distillation. The residue was cooled, then recrystallized in acetone to give the title compound in the yield of 40%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06132462 |
| 出典データセット | uspto-grants-2000_10 |
| ORD ID | ord-597f83e7daa64edfba9d0c5f2eea233c |
| 出典メモ | uspto-grants-2000_10 |