Dimethylformamide diethylacetal → HCID 54074535、化合物

反応式

[CH3:1][C:2]1([CH3:15])[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[C:5](=[O:14])[CH2:4][CH2:3]1.C(O[CH:19](OCC)[N:20]([CH3:22])[CH3:21])C>>[CH3:1][C:2]1([CH3:15])[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[C:5](=[O:14])[C:4](=[CH:19][N:20]([CH3:22])[CH3:21])[CH2:3]1

参加物

反応物 2

HCID 70913Dimethylformamide diethylacetal

HCID 3167867-Methoxy-4,4-dimethyl-3,4-dihydronaphthalen-1(2H)-one

生成物 1

HCID 54074535HCID 54074535、化合物

実験手順

The 3,4-dihydro-4,4-dimethyl-2-dimethylaminomethylene-7-methoxy-1 (2H) naphthalenone was prepared from 4,4-dimethyl-7-methoxy-1-tetralone [2.3 g; H. Hart et al J. Chem. Soc. 85, 3260, (1963)] and N,N-dimethylformamide diethylacetal (6 ml) in a method analogous to that used in Example 1, to give the desired product as a yellow solid (2.26 g) m.p. 108-110°. MS (ES+) 260 (MH+, 100%).

出典と根拠

ORDレコード: ord-4ac5f4454d644281bb231d719aa19ca0
出典データセット: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06133257

反応ノート

読み込み中…

参加物