Hydrochloric Acid → Finafloxacin hydrochloride
反応式
[C:1]([C:3]1[C:4]([N:21]2[CH2:29][C@H:28]3[C@@H:23]([NH:24][CH2:25][CH2:26][O:27]3)[CH2:22]2)=[C:5]([F:20])[CH:6]=[C:7]2[C:12]=1[N:11]([CH:13]1[CH2:15][CH2:14]1)[CH:10]=[C:9]([C:16]([OH:18])=[O:17])[C:8]2=[O:19])#[N:2].[ClH:30]>O>[ClH:30].[C:1]([C:3]1[C:4]([N:21]2[CH2:29][C@H:28]3[C@@H:23]([NH:24][CH2:25][CH2:26][O:27]3)[CH2:22]2)=[C:5]([F:20])[CH:6]=[C:7]2[C:12]=1[N:11]([CH:13]1[CH2:15][CH2:14]1)[CH:10]=[C:9]([C:16]([OH:18])=[O:17])[C:8]2=[O:19])#[N:2]参加物
4
実験手順
1 g (2.5 mmol) of 8-cyano-1-cyclopropyl-6-fluoro-7-((1S,6S)-2-oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid is suspended in 20 ml of water, and the suspension is treated with 10 ml of 1N hydrochloric acid and stirred at room temperature for 3 hours. The precipitate obtained is filtered off with suction, washed with ethanol and dried at 80° C. in a high vacuum.
後処理
- custom