Bas 09531330 → 4H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-chlorophenyl)amino]-

反応式

CC1C=CC(NC2SC3N=CC=CC=3C(=O)N=2)=CC=1.Cl[C:21]1[N:39]=[CH:38][CH:37]=[CH:36][C:22]=1[C:23]([NH:25][C:26]([NH:28][C:29]1[CH:34]=[CH:33][C:32]([Cl:35])=[CH:31][CH:30]=1)=[S:27])=[O:24]>>[Cl:35][C:32]1[CH:33]=[CH:34][C:29]([NH:28][C:26]2[S:27][C:21]3[N:39]=[CH:38][CH:37]=[CH:36][C:22]=3[C:23](=[O:24])[N:25]=2)=[CH:30][CH:31]=1

参加物

反応物 2

HCID 973891Bas 09531330

HCID 232875991-(2-Chloronicotinoyl)-3-(4-chlorophenyl)thiourea

生成物 1

HCID 42920704H-Pyrido[3,2-e]-1,3-thiazin-4-one, 2-[(4-chlorophenyl)amino]-収率 99.7%

実験手順

The reaction procedure of (2) of Example 1 was followed except that 6.19 g (19 mmol) of 1-(2-chloronicotinoyl)-3-(4-chlorophenyl)thiourea was used. As a result, 5.49 g of 2-(4-chloroanilino)-4H-pyrido[3,2-e]-1,3-thiazin-4-one was obtained.

出典と根拠

ORDレコード: ord-475f0d45dae24f3e86cd31a15cc71f43
出典データセット: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06133258

反応ノート

読み込み中…