Benzylamine → 2-Chloro-5-methyl-4-benzylamino-thieno-[2,3-d]-pyrimidine

反応式

[CH2:1]([NH2:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:9][C:10]1[N:11]=[C:12](Cl)[C:13]2[C:18]([CH3:19])=[CH:17][S:16][C:14]=2[N:15]=1>>[Cl:9][C:10]1[N:11]=[C:12]([NH:8][CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[C:13]2[C:18]([CH3:19])=[CH:17][S:16][C:14]=2[N:15]=1

参加物

反応物 2

HCID 7504Benzylamine

HCID 122252992,4-Dichloro-5-methylthieno(2,3-d)pyrimidine

生成物 1

HCID 158951172-Chloro-5-methyl-4-benzylamino-thieno-[2,3-d]-pyrimidine

実験手順

Following the procedure of Example 1, the reaction of benzylamine with 2,4-dichloro-5-methyl-thieno-[2,3-d]-pyrimidine yields 2-chloro-5-methyl-4-benzylamino-thieno-[2,3-d]-pyrimidine.

出典と根拠

ORDレコード: ord-62d83ad4f6f747e397ed4aa637b9d7cc
出典データセット: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06133271

反応ノート

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