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Sodium Cyanide → 4-Chlorobenzonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Cyanide | HCID 8929 | — |
| 反応物 | 4-Chlorobenzene-1-diazonium; tetrafluoroboranuide | HCID 11085506 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 4-Chlorobenzonitrile | HCID 12163 | 75% |
反応手順
Sodium cyanide (2.94 g; 0.06 mol) was added to water and stirred. Cuprous cyanide (2.7 g; 0.03 mol) was added to the mixture stirred until it became homogeneous. 4-chlorobenzenediazonium tetrafluoroborate (5.66 g; 0.025 mol) in water (10 ml) was added to one portion. The mixture was allowed to react at room temperature. The mixture was extracted by ethyl acetate and the extract analysed by means of gas chromatography which indicated that 4-chlorobenzonitrile had been formed in 75% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05416235 |
| 出典データセット | uspto-grants-1995_05 |
| ORD ID | ord-e6b27fd42fc5429c84905e1158cb162b |
| 出典メモ | uspto-grants-1995_05 |