Chlorotriethylsilane → n,n-Diethyl-2-chloro-6-(triethylsilyl)benzamide
反応式
[CH2:1]([N:3]([CH2:13][CH3:14])[C:4](=[O:12])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[Cl:11])[CH3:2].Cl[Si:16]([CH2:21][CH3:22])([CH2:19][CH3:20])[CH2:17][CH3:18]>>[CH2:13]([N:3]([CH2:1][CH3:2])[C:4](=[O:12])[C:5]1[C:10]([Si:16]([CH2:21][CH3:22])([CH2:19][CH3:20])[CH2:17][CH3:18])=[CH:9][CH:8]=[CH:7][C:6]=1[Cl:11])[CH3:14]参加物
3
実験手順
The title compound was prepared according to General Method A from the compound of Example e and 1.4 eq chlorotriethylsilane. Purification by HPLC with 1:19 ethyl acetate/hexanes gave 6.0 g of the desired product as a clear oil, a 92% yield.
後処理
- customThe title compound was prepared
- customPurification by HPLC with 1:19 ethyl acetate/hexanes
出典と根拠
- ORDレコード
- ord-964a76a7c96a4af4b5016d01d8c6ca28
- 出典データセット
- uspto-grants-2000_10
- 特許番号
- US06133252
反応ノート
読み込み中…