化工社化工社 化学情報印刷レポート · 研究参考用
Ethoxyethylamine → N-(2-ethoxyethyl)-2-chloro-6-(trimethylsilyl)benzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethoxyethylamine | HCID 66970 | — |
| 反応物 | 2-Chloro-6-(trimethylsilyl)benzoyl chloride | HCID 15183557 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | N-(2-ethoxyethyl)-2-chloro-6-(trimethylsilyl)benzamide | HCID 18630026 | 66.2% |
反応手順
The compound of Example b (4.94 g, 20 mmol), 2-ethoxyethyl amine (3.92 g, 44 mmol), and toluene (35 mL) were combined according to General Method E1. The crude product was recrystallized from aq ethanol to afford 3.97 g of N-(2-ethoxyethyl)-2-chloro-6-(trimethylsilyl)benzamide as white solid, a 66% yield. m.p. 71-73° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06133252 |
| 出典データセット | uspto-grants-2000_10 |
| ORD ID | ord-7c7469ef38f34e528b1eecd2407de8d7 |
| 出典メモ | uspto-grants-2000_10 |